| Tuesday December 2nd, 2025 |
| Teams | Visitor | Score | Home | Score | W-L | Time | Alternate Location | Game Box |
| McNicholas at Roger Bacon | McNicholas | 61 | Roger Bacon | 27 | W | 6:00 | | Box Score |
| Friday December 5th, 2025 |
| Teams | Visitor | Score | Home | Score | W-L | Time | Alternate Location | Game Box |
| McNicholas at Chaminade Julienne | McNicholas | 47 | Chaminade Julienne | 45 | W | 6:00 | | Box Score |
| Tuesday December 9th, 2025 |
| Teams | Visitor | Score | Home | Score | W-L | Time | Alternate Location | Game Box |
| Badin at McNicholas | Badin | | McNicholas | | W | 6:00 | | Box Score |
| Friday December 12th, 2025 |
| Teams | Visitor | Score | Home | Score | W-L | Time | Alternate Location | Game Box |
| McNicholas at Fenwick | McNicholas | | Fenwick | | W | 6:00 | | Box Score |
| Friday December 19th, 2025 |
| Teams | Visitor | Score | Home | Score | W-L | Time | Alternate Location | Game Box |
| Pitt North Catholic at McNicholas | Pitt North Catholic | | McNicholas | | W | TBA | | Box Score |
| Saturday December 20th, 2025 |
| Teams | Visitor | Score | Home | Score | W-L | Time | Alternate Location | Game Box |
| Elder at McNicholas | Elder | | McNicholas | | W | TBA | | Box Score |
| Monday December 22nd, 2025 |
| Teams | Visitor | Score | Home | Score | W-L | Time | Alternate Location | Game Box |
| McNicholas at Newport Cent. Cath. | McNicholas | | Newport Cent. Cath. | | W | 6:00 | | Box Score |
| Sunday December 28th, 2025 |
| Teams | Visitor | Score | Home | Score | W-L | Time | Alternate Location | Game Box |
| McNicholas at Mason | McNicholas | | Mason | | W | TBA | | Box Score |
| Saturday January 3rd, 2026 |
| Teams | Visitor | Score | Home | Score | W-L | Time | Alternate Location | Game Box |
| McNicholas at St. Xavier | McNicholas | | St. Xavier | | W | 3:30 | | Box Score |
| Tuesday January 6th, 2026 |
| Teams | Visitor | Score | Home | Score | W-L | Time | Alternate Location | Game Box |
| Alter at McNicholas | Alter | | McNicholas | | W | 6:00 | | Box Score |
| Friday January 9th, 2026 |
| Teams | Visitor | Score | Home | Score | W-L | Time | Alternate Location | Game Box |
| Carroll at McNicholas | Carroll | | McNicholas | | W | 6:00 | | Box Score |
| Tuesday January 13th, 2026 |
| Teams | Visitor | Score | Home | Score | W-L | Time | Alternate Location | Game Box |
| McNicholas at LaSalle | McNicholas | | LaSalle | | W | 6:00 | | Box Score |
| Friday January 16th, 2026 |
| Teams | Visitor | Score | Home | Score | W-L | Time | Alternate Location | Game Box |
| Chaminade Julienne at McNicholas | Chaminade Julienne | | McNicholas | | W | 6:00 | | Box Score |
| Saturday January 17th, 2026 |
| Teams | Visitor | Score | Home | Score | W-L | Time | Alternate Location | Game Box |
| McNicholas at Anderson | McNicholas | | Anderson | | W | 2:15 | | Box Score |
| Tuesday January 20th, 2026 |
| Teams | Visitor | Score | Home | Score | W-L | Time | Alternate Location | Game Box |
| McNicholas at Covington Catholic | McNicholas | | Covington Catholic | | W | 6:00 | | Box Score |
| Friday January 23rd, 2026 |
| Teams | Visitor | Score | Home | Score | W-L | Time | Alternate Location | Game Box |
| McNicholas at Badin | McNicholas | | Badin | | W | 6:00 | | Box Score |
| Friday January 30th, 2026 |
| Teams | Visitor | Score | Home | Score | W-L | Time | Alternate Location | Game Box |
| Fenwick at McNicholas | Fenwick | | McNicholas | | W | 6:00 | | Box Score |
| Saturday January 31st, 2026 |
| Teams | Visitor | Score | Home | Score | W-L | Time | Alternate Location | Game Box |
| Turpin at McNicholas | Turpin | | McNicholas | | W | 6:00 | | Box Score |
| Tuesday February 3rd, 2026 |
| Teams | Visitor | Score | Home | Score | W-L | Time | Alternate Location | Game Box |
| MiamiValleyChristian at McNicholas | MiamiValleyChristian | | McNicholas | | W | 6:00 | | Box Score |
| Friday February 6th, 2026 |
| Teams | Visitor | Score | Home | Score | W-L | Time | Alternate Location | Game Box |
| McNicholas at Alter | McNicholas | | Alter | | W | 6:00 | | Box Score |
| Friday February 13th, 2026 |
| Teams | Visitor | Score | Home | Score | W-L | Time | Alternate Location | Game Box |
| McNicholas at Carroll | McNicholas | | Carroll | | W | 6:00 | | Box Score |
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